Self-organizing neural networks for modeling robust 3D and 4D QSAR: application to dihydrofolate reductase inhibitors.
نویسندگان
چکیده
We have used SOM and grid 3D and 4D QSAR schemes for modeling the activity of a series of dihydrofolate reductase inhibitors. Careful analysis of the performance and external predictivities proves that this method can provide an efficient inhibition model.
منابع مشابه
Generation of QSAR sets with a self-organizing map.
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ورودعنوان ژورنال:
- Molecules
دوره 9 12 شماره
صفحات -
تاریخ انتشار 2004